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Sometimes treatment has been stopped after the inititial dose of intramuscular (i.m.) injections

While no evidence-based studies have evaluated their efficacy, digestive enzymes are often used for the purpose of aiding in digestion of proteins such as gluten and casein

Amino Acid Composition Some amino acids naturally resist degradation

Following administration in preclinical models: Intravenous administration provides immediate systemic availability Intramuscular injection demonstrates absorption with peak levels within 1-2 hours Individual peptide components show variable tissue distribution patterns Blood-brain barrier penetration demonstrated for certain neuropeptide fractions Distribution studies indicate that some peptide components can cross the blood-brain barrier, though the extent varies by molecular weight and specific peptide characteristics

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